The Scientific Name of the plant is Neurolaena Lobata (L.), falling under the family: Asteraceae (daisies). The joint name(s) include tree puntas, gavilana, inaciabi, capitana and Jackass Bitters among others.
Numerous ethnomedical uses exist for the plant species. Animal studies and medical documentation on the plants antimalarial, anthelmintic, antibacterial antiplasmodial and hypoglycemic activities exist, but there are no records of clinical attempts to support the use for any indication.
Clinical data does not validate it. In treating malaria, ethnomedicinal resources are different for the dosage of an N. Lobata leaf concoction. It ranges from three glasses per day for 4 days to a single glass daily before taking breakfast for a whole week. Always make sure that you only apply this product under the supervision of an experienced professional.
Information about efficacy and safety in lactation and pregnancy is missing.
Interactions too are not clearly documented as well as the adverse reactions.
Chemical analysis indicated the presence of pyrrolizidine alkaloids. Toxicity too was not observed in oral doses administered to mice in quantities of about 5000 mg/kg.
The weedy herbaceous plant grows in southern Mexico, through Central America, and in the Northwestern South America. The Caribbean islands are also well populated by the plant species. It has alternate trilobed leaves and grows up to heights of about 1 to 2 meters tall. Flowers are known to compactly grow at the end of the branches and are yellow in color. All the plant portions consist of bitter taste, and when freshly handled, it tends to stain the skin yellow.
Various species of the plant have ethnomedicinal uses. The herb in Mesoamerica treated several diseases such as malaria, dysentery, diabetes and cancer. Hepatic ailments, hypertension, and diabetes were also treated by an infusion of the leaves in Panama. In the province of Darian, it was used as an insect repellent and to curb malaria. In the Caribbean folk medicine, the herb was medicinally used to treat skin diseases, ulcers, gastric pain and as a general pain reliever. The plant has been utilized to treat nervous weaknesses, anemia, and malaria in Guatemala. It has also been used as an antipyretic and tonic as well.
Chemistry even with the many
The main medicinal components if the herb, known as sesquiterpene lactones, is concentrated in the leaf. The leaves also contain the neurolenins and are believed to be the main component responsible for treating dysentery. The neurogenic happen to be very bitter. The germacranolide sesquiterpene lactones include the structural ingredients for anticancer and cytotoxic activities. Neuroligins A and B, however, remained inactive in an animal model that is the sarcoma 180. The plant’s activity against insects and the anti-malarial properties can be attributed to the sesquiterpene content in the plant. The geographical location if the plant happens to dictate a number of sesquiterpene components available in the plant. Coumarins, Flavonoids, mellitic acid, thymols, alkaloids and iridoids too have been found to exist in the plant.